SHIRE PLC: Total Voting Rights

Total Voting Rights 
May 1, 2013 - Shire plc (LSE: SHP, NASDAQ: SHPG) (the "Company"), in accordance
with DTR 5.6.1 of the FSA's Disclosure and Transparency Rules, notifies the
market of the following: 
At close of business on April 30, 2013, the Company's issued ordinary share
capital comprised 555,452,055 ordinary shares of 5 pence each with voting
rights and a further 7,374,182 ordinary shares held in treasury. 
Therefore the total number of voting rights in the Company is 555,452,055. This
is the figure which should be used by shareholders as the denominator for the
calculations by which they will determine if they are required to notify their
interest in, or a change to their interest in, the Company under the Financial
Services Authority's Disclosure and Transparency Rules. 
Tony Guthrie
Deputy Company Secretary 
For further information please contact: 
Investor Relations                                                              
                                                                           
Eric Rojas                              erojas@shire.com     +1 781 482 0999    
                                                                           
Sarah Elton-Farr                        seltonfarr@shire.com +44 1256 894157    
NOTES TO EDITORS 
Shire enables people with life-altering conditions to lead better lives. 
Through our deep understanding of patients' needs, we develop and provide
healthcare in the areas of: 
* Behavioral Health and Gastro Intestinal conditions 


      * Rare Diseases
      * Regenerative Medicine
    as well as other symptomatic conditions treated by specialist physicians.

We aspire to imagine and lead the future of healthcare, creating value for
patients, physicians, policymakers, payors and our shareholders.

www.shire.com


                                                                    
Registered in Jersey, No. 99854, 22 Grenville Street, St Helier, Jersey JE4 8PX 
Press Release                                      
                                               
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-0- May/01/2013 11:00 GMT