STMicroelectronics : A*STAR and Veredus Laboratories Create Market's First Lab-on-Chip for the Detection of Multiple Tropical Infectious Diseases Singapore, April 25, 2013 - The Agency for Science, Technology and Research (A*STAR) and Veredus Laboratories, a leading supplier of innovative molecular diagnostic tools, announced the launch of VereTrop^TM, the first biochip in the molecular diagnostics market that can identify 13 different major tropical diseases from a single blood sample. With its high level of automation, this lab-on-chip diagnostic kit is poised to transform the quality and efficiency of testing tropical infectious diseases, including dengue fever, malaria, chikungunya, and hand, foot and mouth disease, in the field. The lead virologist in this project, Associate Professor Lisa F.P. Ng from A*STAR's Singapore Immunology Network (SIgN) said, "Tropical diseases often reflect common symptoms like fever, and may not be accurately diagnosed early by doctors. This portable test kit is a rapid and reliable method to accurately test for multiple pathogenic targets from just one blood sample in a matter of hours." Together with Prof Laurent Renia, an expert in Malaria Immunobiology at SIgN, the team from SIgN has successfully validated the kit on patient samples in the external fields of Northern Thailand, at the Thai-Myanmar border. Professor François H Nosten, the clinical collaborator at the Oxford Clinical Unit in Mae Sot and Director of the Shoklo Malaria Research Unit said, "This technology opens new possibilities for the accurate and rapid diagnostic of important infectious diseases that remain the main causes of illness in the tropics. Its versatility and ease of use will change the approach to diagnostics at the periphery of health care system." Developed with infectious disease expertise from A*STAR's SIgN, this biochip, which operates on STMicroelectronics' Lab-on-Chip platform, was initiated between ETPL, the technology transfer arm of A*STAR, and Veredus in 2009^. Prior to this, Veredus had licensed diagnostic technology from A*STAR in the areas of influenza and malaria^. "Veredus and A*STAR have worked on several collaborative projects dating back to 2004," said Dr. Rosemary Tan, CEO of Veredus Laboratories, a Singapore-based, majority owned subsidiary of STMicroelectronics. "This latest project on VereTrop Lab-on-Chip has combined the strengths and expertise of A*STAR, Veredus, and STMicroelectronics to create a powerful multiplexed molecular product that can rapidly detect and differentiate symptomatically similar tropical infectious diseases and enable timely proper treatment." "After this journey of more than three years, we are glad that such a compelling technologically-advanced product with global healthcare benefits is ready to be launched to the market. Veredus is a good example of how local companies can work with A*STAR for a consistent stream of technology to develop products that can enhance their offerings and level them up to be competitive and relevant globally," said Philip Lim, Chief Executive Officer of ETPL. Enclosed: Annex A - List of tropical diseases that can be detected by VereTrop^TM For media queries, please contact: Agency for Science, Technology and Research (A*STAR) Dr. Sarah Chang Tel: (65) 6826 6442 Email: email@example.com ETPL (A*STAR's Technology Transfer arm) Ms. Amanda Lee DID: (65) 6478 8443 Email: firstname.lastname@example.org Veredus Laboratories Mr. Boey Taik Boon Corporate External Communications STMicroelectronics Asia-Pacific Tel: +65 6427 7765 Email: email@example.com About the Agency for Science, Technology and Research (A*STAR) The Agency for Science, Technology and Research (A*STAR) is Singapore's lead public sector agency that fosters world-class scientific research and talent to drive economic growth and transform Singapore into a vibrant knowledge-based and innovation driven economy. In line with its mission-oriented mandate, A*STARspearheads research and development in fields that are essential to growing Singapore's manufacturing sector and catalysing new growth industries. A*STAR supports these economic clusters by providing intellectual, human and industrial capital to its partners in industry. A*STAR oversees 20 biomedical sciences and physical sciences and engineering research entities, located in Biopolis and Fusionopolis as well as their vicinity. These two R&D hubs house a bustling and diverse community of local and international research scientists and engineers from A*STAR's research entities as well as a growing number of corporate laboratories. For more information about A*STAR, please visitwww.a-star.edu.sg About ETPL ETPL is the technology transfer arm of the Agency for Science, Technology and Research (A*STAR), Singapore's lead agency for fostering world-class scientific research and talent. A*STAR oversees 14 biomedical sciences, physical sciences and engineering research institutes, and six consortia and centres. As a one-stop resource, ETPL supports A*STAR in transforming the economy through driving innovation and commercializing its research outcomes. Also known as Exploit Technologies Pte Ltd, ETPL enhances the research output of A*STAR scientists by translating their inventions into marketable products or processes. Through shaping and facilitating licensing deals and spin-offs, ETPL actively engages industry leaders and players to commercialise A*STAR's technologies and apply them to building ecosystems that benefit business, industry and economy. For more information, please visit http://etpl.sg About Veredus Laboratories Pte Ltd Veredus Laboratories Pte Ltd was founded in 2003 and launched its first products in 2005. Veredus is a Singapore-based majority-owned subsidiary of STMicroelectronics (NYSE: STM), a global semiconductor leader serving customers across the spectrum of electronics applications. Veredus specializes in the development, manufacture, and marketing of innovative multiplexed molecular solutions in the clinical, specialty, and custom testing markets based on STMicroelectronics' proprietary Lab-on-Chip platform. The Lab-on-Chip platform, marketed as the VerePLEX^TM Biosystem, combines Micro-Electro-Mechanical-Systems (MEMS) with micro-fluidics to integrate multiplexed DNA amplification with microarray detection for rapid, cost-effective, and accurate analysis of biological materials. Further information on Veredus can be found at www.vereduslabs.com. About STMicroelectronics ST is a global leader in the semiconductor market serving customers across the spectrum of sense and power and automotive products and embedded processing solutions. From energy management and savings to trust and data security, from healthcare and wellness to smart consumer devices, in the home, car and office, at work and at play, ST is found everywhere microelectronics make a positive and innovative contribution to people's life. By getting more from technology to get more from life, ST stands for life.augmented. In 2012, the Company's net revenues were $8.49 billion. Further information on ST can be found at www.st.com. ANNEX A List of 13 Tropical Diseases and corresponding sub-species detected by VereTrop^TM To detect Disease To Subspecies discriminate African Trypanosoma.brucei rhodensiense trypanosomiasis 1 (T.Br)/ Trypanosoma.brucei 1 (Sleeping Sickness) gambiense (T.Bg) Human American trypanosomiasis 2 Trypanosoma.cruzi cruzi (T.Cc) (Chagas disease) 3 Plasmodium falciparum (P.fal) 4 Plasmodium vivax (P.viv) 2 Malaria 5 Plasmodium ovale (P.O) 6 Plasmodium malariae (P.m) 7 Plasmodium knowlesi (P.kn) 3 Typhoid Fever 8 Salmonella typhi (ST) Leptospira.interrogans Leptospira.borgpetersenenii Leptospirosis Leptospira.weilii 4 (Weil's syndrome) 9 Leptospira.santorosai Leptospira.alexanderi Leptospira.noguchii Leptospira. kirschneri 5 Melioidosis 10 Burkholderia pseudomallei (BP) 6 Chikungunya Fever 11 Chikungunya virus (CHIKV) 12 Dengue serotype 1 virus (DENV 1) 7 Dengue Fever 13 Dengue serotype 2 virus (DENV 2) 14 Dengue serotype 3 virus (DENV 3) 15 Dengue serotype 4 virus (DENV 4) 8 West Nile 16 West Nile Virus (WNV) 9 Yellow Fever 17 Yellow Fever Virus (YFV) 10 Japanese 18 Japanese Encephalitis Virus (JEV) Encephalitis 11 Rift Valley Fever 19 Rift Valley Virus (RVV) 12 Hand, foot and mouth 20 Human enterovirus A EV-71 (EV71) disease (HFMD) 21 Puumala virus (PUUV) Hemorrhagic fever 22 Tula virus (TULV) with renal syndrome 23 Dobrava-Belgrade virus (DOBV) (HFRS) 24 Seoul virus (SEOV) 13 25 Hantaan virus (HTNV) Hantavirus Cardiopulmonary 26 Andes virus (ANDV) Syndrome (HCPS or HPS) -------------------------  ETPL funded the project from the onset - designing the sequence probes, developing and validating the chip, up to acquiring samples for clinical validation.  http://www.a-star.edu.sg/Media/News/PressReleases/tabid/828/articleType/ArticleView/articleId/91/Default.aspx VereTrop PR VereTrop PR_IMAGE ------------------------------------------------------------------------------ This announcement is distributed by Thomson Reuters on behalf of Thomson Reuters clients. The owner of this announcement warrants that: (i) the releases contained herein are protected by copyright and other applicable laws; and (ii) they are solely responsible for the content, accuracy and originality of the information contained therein. Source: STMicroelectronics via Thomson Reuters ONE HUG#1696162
STMicroelectronics : A*STAR and Veredus Laboratories Create Market's First Lab-on-Chip for the Detection of Multiple Tropical
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