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STMicroelectronics : A*STAR and Veredus Laboratories Create Market's First Lab-on-Chip for the Detection of Multiple Tropical

  STMicroelectronics : A*STAR and Veredus Laboratories Create Market's First
    Lab-on-Chip for the Detection of Multiple Tropical Infectious Diseases

Singapore, April 25, 2013 - The Agency for Science, Technology and Research
(A*STAR) and Veredus Laboratories, a leading supplier of innovative molecular
diagnostic tools, announced the launch of VereTrop^TM, the first biochip in
the molecular diagnostics market that can identify 13 different major tropical
diseases from a single blood sample.

With its high level of automation, this lab-on-chip diagnostic kit is poised
to transform the quality and efficiency of testing tropical infectious
diseases, including dengue fever, malaria, chikungunya, and hand, foot and
mouth disease, in the field.

The lead virologist in this project, Associate Professor Lisa F.P. Ng from
A*STAR's Singapore Immunology Network (SIgN) said, "Tropical diseases often
reflect common symptoms like fever, and may not be accurately diagnosed early
by doctors. This portable test kit is a rapid and reliable method to
accurately test for multiple pathogenic targets from just one blood sample in
a matter of hours."

Together with Prof Laurent Renia, an expert in Malaria Immunobiology at SIgN,
the team from SIgN has successfully validated the kit on patient samples in
the external fields of Northern Thailand, at the Thai-Myanmar border.

Professor François H Nosten, the clinical collaborator at the Oxford Clinical
Unit in Mae Sot and Director of the Shoklo Malaria Research Unit said, "This
technology opens new possibilities for the accurate and rapid diagnostic of
important infectious diseases that remain the main causes of illness in the
tropics. Its versatility and ease of use will change the approach to
diagnostics at the periphery of health care system."

Developed with infectious disease expertise from A*STAR's SIgN, this biochip,
which operates on STMicroelectronics' Lab-on-Chip platform, was initiated
between ETPL, the technology transfer arm of A*STAR, and Veredus in 2009^[1].
Prior to this, Veredus had licensed diagnostic technology from A*STAR in the
areas of influenza and malaria^[2].

"Veredus and A*STAR have worked on several collaborative projects dating back
to 2004," said Dr. Rosemary Tan, CEO of Veredus Laboratories, a
Singapore-based, majority owned subsidiary of STMicroelectronics. "This
latest project on VereTrop Lab-on-Chip has combined the strengths and
expertise of A*STAR, Veredus, and STMicroelectronics to create a powerful
multiplexed molecular product that can rapidly detect and differentiate
symptomatically similar tropical infectious diseases and enable timely proper
treatment."

"After this journey of more than three years, we are glad that such a
compelling technologically-advanced product with global healthcare benefits is
ready to be launched to the market. Veredus is a good example of how local
companies can work with A*STAR for a consistent stream of technology to
develop products that can enhance their offerings and level them up to be
competitive and relevant globally," said Philip Lim, Chief Executive Officer
of ETPL.

Enclosed:

Annex A - List of tropical diseases that can be detected by VereTrop^TM

For media queries, please contact:

Agency for Science, Technology and Research (A*STAR)
Dr. Sarah Chang
Tel: (65) 6826 6442
Email: chang_kai_chen@a-star.edu.sg

ETPL (A*STAR's Technology Transfer arm)
Ms. Amanda Lee
DID: (65) 6478 8443
Email: amanda_lee@etpl.sg

Veredus Laboratories
Mr. Boey Taik Boon
Corporate External Communications
STMicroelectronics Asia-Pacific
Tel: +65 6427 7765
Email: taik-boon.boey@st.com

About the Agency for Science, Technology and Research (A*STAR)

The Agency for Science, Technology and Research (A*STAR) is Singapore's lead
public sector agency that fosters world-class scientific research and talent
to drive economic growth and transform Singapore into a vibrant
knowledge-based and innovation driven economy.

In line with its mission-oriented mandate, A*STARspearheads research and
development in fields that are essential to growing Singapore's manufacturing
sector and catalysing new growth industries. A*STAR supports these economic
clusters by providing intellectual, human and industrial capital to its
partners in industry.

A*STAR oversees 20 biomedical sciences and physical sciences and engineering
research entities, located in Biopolis and Fusionopolis as well as their
vicinity. These two R&D hubs house a bustling and diverse community of local
and international research scientists and engineers from A*STAR's research
entities as well as a growing number of corporate laboratories. For more
information about A*STAR, please visitwww.a-star.edu.sg



About ETPL

ETPL is the technology transfer arm of the Agency for Science, Technology and
Research (A*STAR), Singapore's lead agency for fostering world-class
scientific research and talent. A*STAR oversees 14 biomedical sciences,
physical sciences and engineering research institutes, and six consortia and
centres. As a one-stop resource, ETPL supports A*STAR in transforming the
economy through driving innovation and commercializing its research outcomes.

Also known as Exploit Technologies Pte Ltd, ETPL enhances the research output
of A*STAR scientists by translating their inventions into marketable products
or processes. Through shaping and facilitating licensing deals and spin-offs,
ETPL actively engages industry leaders and players to commercialise A*STAR's
technologies and apply them to building ecosystems that benefit business,
industry and economy. For more information, please visit http://etpl.sg

About Veredus Laboratories Pte Ltd

Veredus Laboratories Pte Ltd was founded in 2003 and launched its first
products in 2005. Veredus is a Singapore-based majority-owned subsidiary of
STMicroelectronics (NYSE: STM), a global semiconductor leader serving
customers across the spectrum of electronics applications.

Veredus specializes in the development, manufacture, and marketing of
innovative multiplexed molecular solutions in the clinical, specialty, and
custom testing markets based on STMicroelectronics' proprietary Lab-on-Chip
platform. The Lab-on-Chip platform, marketed as the VerePLEX^TM Biosystem,
combines Micro-Electro-Mechanical-Systems (MEMS) with micro-fluidics to
integrate multiplexed DNA amplification with microarray detection for rapid,
cost-effective, and accurate analysis of biological materials.
Further information on Veredus can be found at www.vereduslabs.com.

About STMicroelectronics

ST is a global leader in the semiconductor market serving customers across the
spectrum of sense and power and automotive products and embedded processing
solutions. From energy management and savings to trust and data security, from
healthcare and wellness to smart consumer devices, in the home, car and
office, at work and at play, ST is found everywhere microelectronics make a
positive and innovative contribution to people's life. By getting more from
technology to get more from life, ST stands for life.augmented.

In 2012, the Company's net revenues were $8.49 billion. Further information on
ST can be found at www.st.com.

ANNEX A

List of 13 Tropical Diseases and corresponding sub-species detected by
VereTrop^TM

To detect       Disease             To                  Subspecies
                               discriminate
                African                      Trypanosoma.brucei rhodensiense
            trypanosomiasis         1           (T.Br)/ Trypanosoma.brucei
    1     (Sleeping Sickness)                        gambiense (T.Bg)
             Human American
            trypanosomiasis         2         Trypanosoma.cruzi cruzi (T.Cc)
            (Chagas disease)
                                    3         Plasmodium falciparum (P.fal)
                                    4            Plasmodium vivax (P.viv)
    2           Malaria             5             Plasmodium ovale (P.O)
                                    6           Plasmodium malariae (P.m)
                                    7           Plasmodium knowlesi (P.kn)
    3        Typhoid Fever          8             Salmonella typhi (ST)
                                                  Leptospira.interrogans
                                               Leptospira.borgpetersenenii
             Leptospirosis                          Leptospira.weilii
    4      (Weil's syndrome)        9             Leptospira.santorosai
                                                  Leptospira.alexanderi
                                                   Leptospira.noguchii
                                                  Leptospira. kirschneri
    5         Melioidosis           10        Burkholderia pseudomallei (BP)
    6      Chikungunya Fever        11          Chikungunya virus (CHIKV)
                                    12       Dengue serotype 1 virus (DENV 1)
    7         Dengue Fever          13       Dengue serotype 2 virus (DENV 2)
                                    14       Dengue serotype 3 virus (DENV 3)
                                    15       Dengue serotype 4 virus (DENV 4)
    8          West Nile            16            West Nile Virus (WNV)
    9         Yellow Fever          17           Yellow Fever Virus (YFV)
   10           Japanese            18      Japanese Encephalitis Virus (JEV)
              Encephalitis
   11      Rift Valley Fever        19           Rift Valley Virus (RVV)
   12     Hand, foot and mouth      20       Human enterovirus A EV-71 (EV71)
             disease (HFMD)
                                    21             Puumala virus (PUUV)
           Hemorrhagic fever        22              Tula virus (TULV)
          with renal syndrome       23        Dobrava-Belgrade virus (DOBV)
                 (HFRS)             24              Seoul virus (SEOV)
   13                               25             Hantaan virus (HTNV)
               Hantavirus
            Cardiopulmonary         26              Andes virus (ANDV)
           Syndrome (HCPS or
                  HPS)

-------------------------

[1] ETPL funded the project from the onset - designing the sequence probes,
developing and validating the chip, up to acquiring samples for clinical
validation.

[2]
http://www.a-star.edu.sg/Media/News/PressReleases/tabid/828/articleType/ArticleView/articleId/91/Default.aspx

VereTrop PR
VereTrop PR_IMAGE

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