HIV Researchers Celebrate 20 Years of Collaboration

HIV Researchers Celebrate 20 Years of Collaboration

KANSAS CITY, Mo., April 23, 2013 (GLOBE NEWSWIRE) -- The HIV Outpatient Study
(HOPS), supported by Cerner's Infectious Disease Insights group, HIV clinic
researchers, and the dedicated project team from the Centers for Disease
Control and Prevention (CDC) will be celebrating its 20th Anniversary during
the Annual HOPS Investigator meeting held in April in Tampa, Fla.

HOPS, one of the largest U.S. government-funded longitudinal cohort studies,
follows HIV-infected patients to gain insights to improve prevention and
treatment of HIV/AIDS. CDC initiated the study in 1993 to describe and monitor
trends in demographics, symptoms, diagnoses, and treatments in a population of
HIV-infected outpatients in nine clinics across the United States. HOPS
researchers at these clinics gather clinical, immunologic and virologic data,
as well as genotypic and phenotypic information through periodic reviews of
medical records.

Through analysis of HOPS data, researchers have verified the impact of
existing therapeutics, gained knowledge to inform new best practices in
prevention and treatment and discovered new concerns warranting additional
study. To date, researchers have shared HOPS study findings through 56
published manuscripts and 115 abstracts and presentations, thus enhancing the
medical community's understanding of prolonged survival, the metabolic
problems associated with combination antiretroviral therapy (cART), adherence
to cART, and the occurrence of comorbidities.

"HOPS is a unique study that highlights the power of true collaboration," said
Dr. Sam Bozzette, a Cerner executive and internationally-recognized HIV
researcher who provides strategic oversight to Cerner's HOPS team. "HOPS is
designed to encourage the exchange of ideas among the research stakeholders
from the CDC and participating clinic sites and provides them with the
flexibility and agility to explore concerns and ideas as they become
apparent."

Dr. John T. Brooks, the medical epidemiologist in CDC's Division of HIV/AIDS
Prevention who oversees the study, commented, "HOPS has been instrumental in
highlighting the health challenges faced by persons living with HIV in the
United States. He added, "Through analyses of data from more than 9,000
HIV-infected patients who volunteered to participate in this research from
1993 to date, we have been able to document new complications associated with
chronic HIV disease such as cardiovascular and bone disorders. We also
continue to demonstrate the value of cART and preventative strategies for
extending and improving patients' lives."

Cerner plays a significant role in HOPS by collecting and managing the study
data, ensuring quality assurance, conducting analysis and providing clinical
and research expertise. Study personnel at the clinic sites and data managers
in Cerner's coordinating center use Discovere^®, Cerner's Web-based research
platform, to streamline their research activities. Kathy Wood, Cerner's
research project leader for the study, is a co-author on many of the HOPS
publications.

In recognizing this HOPS 20th Anniversary milestone, CDC, Cerner, site
investigators, and research consultants underscore how research benefits
clinicians, patients and their loved ones by providing insights to improve
health and care.

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