Research shows that superbugs are killed by ACTICOAT™ silver-coated antimicrobial dressings ST. PETERSBURG, Fla., April 9, 2013 /CNW/ - Smith & Nephew (LSE: SN, NYSE: SNN), the global medical technology business, today announced in-vitro study results suggesting ACTICOAT Silver-Coated Antimicrobial Dressings are bactericidal against some antibiotic resistant organisms carrying the NDM-1 enzyme, often referred to as 'superbugs'. An in-vitro laboratory study showed ACTICOAT Dressings, containing patented Nanocrystalline Silver technology, can kill the antibiotic resistant enzyme, New Delhi metallo-beta-lactamase 1 (NDM-1 bacteria strain)(3) which is carried by four of the same CRE bacteria cited by the CDC1. In this study, ACTICOAT Dressings killed Escherichia coli and Klebsiella spp.,(3) which are responsible for most carbapenem resistance in the United States(1). The Centers for Disease Control (CDC) issued statements recently to warn the public about antibiotic resistant organisms like carbapenem-resistant Enterobacteriaceae (CRE), raising concerns about the rise in the prevalence of these organisms and their associated high mortality rates(1). While the prevalence of CRE varies by geographic region, CRE organisms can spread their resistant genes to common bacteria, potentially resulting in the spread of untreatable infections. Reducing the spread of CRE is challenging for hospitals, rehabilitation facilities and nursing homes because these antibiotic resistant bacteria develop resistance to even the most powerful antibiotics which are often reserved as a last resort. According to the CDC, almost all CRE infections happen to patients who are receiving serious medical care(2). Dr. Jose Vazquez, MD, FACP, FIDSA, Professor of Medicine, Division of Infectious Diseases, Wayne State University School of Medicine, Senior Staff, Henry Ford Hospital, Detroit, MI uses ACTICOAT Dressings in his practice. He says: "Any opening in the skin provides an entry point for antibiotic resistant organisms. I use ACTICOAT Dressings in my practice because they provide an antimicrobial barrier that helps protect wounds and incision sites from external contamination. I continue to see excellent clinical results because ACTICOAT Dressings are bactericidal against five strains of bacteria that carry the NDM-1 enzyme and 360+ pathogens including 188 strains of MRSA." The Nanocrystalline Silver in ACTICOAT Dressings is different from the silvers used in other dressings because of its potency, fast kill action of 30 minutes, and broad spectrum activity. ACTICOAT provides bactericidal activity for up to seven days, so it helps protect patients with wounds or incisions from environmental contamination, even after they leave the hospital. ACTICOAT is contra-indicated in patients with known hypersensitivity to any of the components of the product. (If signs of a sensitivity reaction develop during use, treatment should be discontinued.) "We share the same concerns as the CDC about antibiotic resistant organisms and are pleased that ACTICOAT Dressings are bactericidal against five different strains of bacteria that carry NDM-1 carbapenemases," said Tom Dugan, President, North America, Advanced Wound Management division, Smith & Nephew. "Making this information widely available is part of our obligation to address public health issues and support clinicians and the patients they serve, helping them to reduce the human and economic costs of wounds." For more information about Smith & Nephew, please visit www.smith-nephew.com. References 1) CDC 2012 CRE Toolkit. Guidance for Control of Carbapenem-resistant Enterobacteriaceae. 2) CDC Vital Signs™ Report, March 2013 3) Hope et al. (2012) The In-Vitro antibacterial activity of nanocrystalline silver dressings against bacteria with NDM-1 carbapenemase. Presented at European Wound Management Association Conference. Vienna. About Smith & Nephew Smith & Nephew is a global medical technology business dedicated to helping improve people's lives. With leadership positions in Orthopaedic Reconstruction, Advanced Wound Management, Sports Medicine and Trauma, Smith & Nephew has almost 10,500 employees and a presence in more than 90 countries. Annual sales in 2012 were more than $4.1 billion. Smith & Nephew is a member of the FTSE100 (LSE: SN, NYSE: SNN). For more information about Smith & Nephew, please visit: www.smith-nephew.com Forward-looking Statements This document may contain forward-looking statements that may or may not prove accurate. For example, statements regarding expected revenue growth and trading margins, market trends and our product pipeline are forward-looking statements. Phrases such as "aim", "plan", "intend", "anticipate", "well-placed", "believe", "estimate", "expect", "target", "consider" and similar expressions are generally intended to identify forward-looking statements. Forward-looking statements involve known and unknown risks, uncertainties and other important factors that could cause actual results to differ materially from what is expressed or implied by the statements. For Smith & Nephew, these factors include: economic and financial conditions in the markets we serve, especially those affecting health care providers, payors and customers; price levels for established and innovative medical devices; developments in medical technology; regulatory approvals, reimbursement decisions or other government actions; product defects or recalls; litigation relating to patent or other claims; legal compliance risks and related investigative, remedial or enforcement actions; strategic actions, including acquisitions and dispositions, our success in integrating acquired businesses, and disruption that may result from changes we make in our business plans or organisation to adapt to market developments; and numerous other matters that affect us or our markets, including those of a political, economic, business or competitive nature. Please refer to the documents that Smith & Nephew has filed with the U.S. Securities and Exchange Commission under the U.S. Securities Exchange Act of 1934, as amended, including Smith & Nephew's most recent annual report on Form 20-F, for a discussion of certain of these factors. Any forward-looking statement is based on information available to Smith & Nephew as of the date of the statement. All written or oral forward-looking statements attributable to Smith & Nephew are qualified by this caution. Smith & Nephew does not undertake any obligation to update or revise any forward-looking statement to reflect any change in circumstances or in Smith & Nephew's expectations. Investors/Analysts: Phil Cowdy, Smith & Nephew, +44 (0)20 7401 7646, or Media: Amy Phillips, EVC Group, +1 412 327 9499 http://www.smith-nephew.com SOURCE: Smith & Nephew To view this news release in HTML formatting, please use the following URL: http://www.newswire.ca/en/releases/archive/April2013/09/c3676.html CO: Smith & Nephew ST: Florida NI: HEA MTC ECOSURV -0- Apr/09/2013 11:01 GMT
Research shows that superbugs are killed by ACTICOAT™ silver-coated antimicrobial dressings
Press spacebar to pause and continue. Press esc to stop.