Bio-Modeling Systems and Persistent Systems Launch Joint Strategic Systems Biology Initiative

Bio-Modeling Systems and Persistent Systems Launch Joint Strategic Systems 
Biology Initiative 
R&D Program to Accelerate Mechanism-Based Drug Discovery, Help
Eliminate Use of Animals in Contact Allergy Testing 
PARIS and SANTA CLARA, CA and PUNE, INDIA -- (Marketwire) -- 03/25/13
--  Bio-Modeling Systems (BMSystems), a leading integrative systems
biology company and Persistent Systems (BOMBAY: PERSISTENT) (NSE:
PERSISTENT), the global leader in software product and technology
services, today announced a joint systems biology research and
development initiative. The strategic initiative is the world's first
collaborative effort that marries non-mathematical heuristic modeling
with mathematical modeling designed to increase the success rates of
drug discovery and formulation development by pharmaceutical and
cosmetic industries. A key deliverable of this joint initiative is
the development of a predictive in silico or computer simulated skin
model that will help eliminate the need to use animals in contact
allergy testing. Today's announcement follows on the heels of the
European Union's ban on the import and sale of cosmetics containing
ingredients tested on animals, offering the industry a highly
effective and essential alternative.  
Bio-Modeling Systems' team of highly skilled biologists will combine
the outputs of its CADI*(TM) proprietary heuristic modeling platform
with a powerful new software platform, Cell-in-Silico, developed by
Persistent, resulting in the first heuristic model of skin cell
interplay mechanisms to be enhanced through mathematical modelling.
This strategic collaboration harnesses the scientific and
bioinformatics capabilities of Bio-Modeling Systems and the
information technology and scientific capabilities of Persistent
Systems to provide the first ever truly holistic systems-based drug
discovery solutions. 
"Bio-Modeling Systems and Persistent Systems have come together to
develop a much needed solution that will address the pharma and
cosmetic industries' need for predictive modeling of skin in silico,"
said Dr. Anand Deshpande, Managing Director and CEO, Persistent
Systems. "Bio-Modeling Systems scientists have pioneered heuristic
biological modeling with their CADI(TM)* platform. By coupling this
with Persistent Systems' strength in mathematical modeling and IT, we
will develop a viable in silico alternative to animal testing." 
"We are delighted to partner with Persistent Systems' life sciences
experts, as together we can bridge the gap and powerfully link
complementary heuristic and mathematical modeling," said Manuel Gea,
CEO, Bio-Modeling Systems.  
"For the first time ever, mechanistic modeling and dynamics
engineering will be merged, bringing a whole new level of
understanding to the multi-scale biological space, enabling us to
develop a fully integrated, outstanding set of solutions to
previously intractable biotechnological problems," said Dr. Francois
Iris, CSO, Bio-Modeling Systems. "We look forward to addressing the
industry's challenges head-on with this powerful offering."  
About Bio-Modeling Systems (BMSystems): 
 Bio-Modeling Systems, an
innovative company founded in 2004, is the first and, to date, only
company to successfully create in-silico heuristic models validated
in-vivo. BMSystems' heuristic models, built by its biologists using
an integrated IT solution called CADI (TM) (Computer Assisted
Deductive Integration) have led to discoveries, patents, and
operational businesses in the fields of infectious diseases,
immunology, neurology, psychiatry, oncology, dermatology and
innovative bioprocesses for industrial biotech. BMSystems' models
describe the biological phenomena involved in pathological states and
provide new mechanisms to explain the cause of certain diseases,
identify and select predictive biomarkers, offer new combinations of
molecules and new therapeutic strategies contributing to the
development of Mechanism-Based Medicine.  
For more information, please visit 
About Persistent Systems:
 Established in 1990, Persistent Systems
(BOMBAY: PERSISTENT) (NSE: PERSISTENT) is a global company
specializing in software products and technology services. For more
than two decades, Persistent has been an innovation partner for the
world's largest technology brands, leading enterprises and pioneering
start-ups. With a global team of more than 6,000 employees,
Persistent has 300 customers spread across North America, Europe, and
Asia. Today, Persistent focuses on developing best-in-class solutions
in four key next-generation technology areas: Cloud Computing,
Mobility, Analytics and Collaboration, for telecommunications, life
sciences, consumer packaged goods, banking & financial services and
healthcare verticals. For more information, please visit:  
Forward-looking and Cautionary Statements: For risks and
uncertainties relating to forward-looking statements, please visit: 
All trademarks, trade names, service marks, and logos referenced
herein belong to their respective companies. 
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Media Contacts:
Rashmi Joshi
Persistent Systems, Ltd.
+91 83083 39400 
Ilona Mohacsi
PenVine for Persistent Systems, Inc.
+1 631 764 3729 
Manuel Gea
+33 683061272 
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