Vermillion Appoints Bruce A. Huebner to Chairman of the Board

        Vermillion Appoints Bruce A. Huebner to Chairman of the Board

Shareholders to Vote on Approval of Expanded Stock Incentive Plan at Upcoming
Annual Meeting

PR Newswire

AUSTIN, Texas, March 19, 2013

AUSTIN, Texas, March 19, 2013 /PRNewswire/ --Vermillion, Inc. (NASDAQ: VRML),
a molecular diagnostics company focused on gynecologic cancers and women's
health, has appointed Bruce A. Huebner as chairman effective March 18, 2013.
He succeeds James S. Burns, who will continue to serve on the board of
directors. Huebner's appointment represents an important step in the execution
of the company's leadership succession plan that began in 2012.

Huebner previously served as Vermillion's CEO on an interim basis until the
recent appointment of Thomas McLain to the position of President and Chief
Executive Officer, which also took effect yesterday. Huebner has been a
company director since May 2011.

"Bruce demonstrated highly effective leadership during this transition
period," said Burns. "Given his performance, as well as his more than 37 years
of diagnostic industry experience and history of valuable contributions as a
director, the board believes that the company and its shareholders would
greatly benefit from Bruce as our chairman. I look forward to working closely
with Bruce and our new president to build shareholder value, as we advance
Vermillion as a leading diagnostics company addressing unmet clinical needs in
women's health."

Shareholder Vote
At the company's upcoming 2012 annual meeting on March 21, the board will
request shareholder approval to increase the number of authorized shares in
the company's 2010 stock incentive plan by 1.3 million shares.

"The company currently has only nominal shares available under the 2010 stock
incentive plan," noted Chairman Huebner. "We will need more shares to attract
qualified executives, directors and employees to Vermillion. Without the
approval of these additional shares, we will have to increase the cash
compensation to these individuals. We would also not have the benefit of
incentivized performance that is typically created by a stock option plan, and
one that better aligns the interests of management and employees with that of
our shareholders. So, it is in the best interest of Vermillion shareholders
that we approve the expansion of this plan."

Huebner Career Biography
Bruce Huebner brings to the role of Vermillion's chairman extensive executive
management experience in multiple clinical diagnostic companies, including
Osmetech Molecular Diagnostics, Nanogen and Gen-Probe. While serving as
president of Osmetech, he successfully established the company as a fully
integrated business, obtaining FDA clearance for four molecular diagnostic
microarray products and introducing them to the marketplace. Huebner was
previously president and chief operating officer of Nanogen, a publicly held
nanotechnology and microarray company.

Prior to Nanogen, he was executive vice president and chief operating officer
of Gen-Probe, a global leader in the development of nucleic acid tests,
including diagnostic tests for infectious disease that affect women's health.
In less than 10 years, he grew Gen-Probe's annual revenues from $42 million to
a run-rate of more than $150 million. Huebner is currently a managing director
of LynxCom Partners, a healthcare consulting firm with a focus on cancer
diagnostics and personalized medicine.

About Vermillion
Vermillion, Inc. (NASDAQ: VRML) is dedicated to the discovery, development and
commercialization of novel high-value diagnostic tests that help physicians
diagnose, treat and improve outcomes for patients. Vermillion, along with its
prestigious scientific collaborators, has diagnostic programs in oncology,
vascular medicine and women's health.

The company's lead diagnostic, OVA1®, is a blood test for pre-surgical
assessment of tumors for malignancy, using a unique multi-biomarker approach.
In a published clinical trial, OVA1 achieved 99% sensitivity in detecting
epithelial ovarian cancers (EOC). This included 96% sensitivity for stage I
EOC, the earliest and most curable EOC stage, compared with 57% for the
conventional biomarker CA125. In addition, OVA1 found 70% of malignancies
missed by non-specialist pre-surgical assessment, and it increased detection
of malignancy over ACOG guidelines from 77% to 94%. As the first
protein-based, In Vitro Diagnostic Multi-Variate Index Assay (IVDMIA) cleared
by the FDA, OVA1 also represents a new class of software-based diagnostics.
Additional information about these published clinical trials is available on
Vermillion's website at

Forward-Looking Statement
Certain matters discussed in this press release contain forward-looking
statements that involve significant risks and uncertainties, including
statements regarding Vermillion's plans, objectives, expectations and
intentions. These forward-looking statements are based on Vermillion's current
expectations. The Private Securities Litigation Reform Act of 1995 provides a
"safe harbor" for such forward-looking statements. In order to comply with the
terms of the safe harbor, Vermillion notes that a variety of factors could
cause actual results and experience to differ materially from the anticipated
results or other expectations expressed in such forward-looking statements.
Factors that could cause actual results to materially differ include but are
not limited to: (1) uncertainty as to Vermillion's ability to protect and
promote its proprietary technology; (2) Vermillion's lack of a lengthy track
record successfully developing and commercializing diagnostic products; (3)
uncertainty as to whether Vermillion will be able to obtain any required
regulatory approval of its future diagnostic products; (4) uncertainty of the
size of market for its existing diagnostic tests or future diagnostic
products, including the risk that its products will not be competitive with
products offered by other companies, or that users will not be entitled to
receive adequate reimbursement for its products from third party payors such
as private insurance companies and government insurance plans; (5) uncertainty
that Vermillion has sufficient cash resources to fully commercialize its tests
and continue as a going concern; (6) uncertainty whether the trading in
Vermillion's stock will become significantly less liquid; and (7) other
factors that might be described from time to time in Vermillion's filings with
the U.S. Securities and Exchange Commission (SEC). All information in this
press release is as of the date of this report, and Vermillion expressly
disclaims any obligation or undertaking to release publicly any updates or
revisions to any such statements to reflect any change in Vermillion's
expectations or any change in events, conditions or circumstances on which any
such statement is based, unless required by law.

This release should be read in conjunction with the consolidated financial
statements and notes thereto included in the company's most recent reports on
Form 10-K and Form 10-Q. Copies are available through the SEC's Electronic
Data Gathering Analysis and Retrieval system (EDGAR) at

Investor Relations Contact
Liolios Group, Inc.
Ron Both
Tel 1-949-574-3860

SOURCE Vermillion, Inc.

Press spacebar to pause and continue. Press esc to stop.