Personalis Awarded Contract From VA Million Veteran Program – Whole Genome Sequencing and Data Analysis for Over 1,000

  Personalis Awarded Contract From VA Million Veteran Program – Whole Genome
  Sequencing and Data Analysis for Over 1,000 Individuals

Business Wire

MENLO PARK, Calif. -- March 12, 2013

The US Department of Veterans Affairs (VA) has awarded its first contract for
whole genome DNA sequencing and data analysis to Personalis, Inc., of Menlo
Park, CA. The contract will utilize samples from several VA sources, including
from the Million Veteran Program (MVP). Using its secure computing facility
and proprietary algorithms, Personalis will QC all raw data, call variants
against an advanced human reference sequence, annotate both SNV/indels and
SVs, and provide genetic analyses to help confirm sample / data chain of
custody. Personalis plans to subcontract the laboratory genetic analysis,
including both DNA sequencing and genome-scale genotyping, to Illumina, Inc.,
of San Diego, CA.

Personalis CEO John West said “The VA’s MVP has the potential to be the
largest and most important medical sequencing effort in the world. We are
thrilled that the VA has chosen Personalis for the DNA sequencing and analysis
on this project. Our emphasis is on delivering an accurate and comprehensive
sequencing solution for the VA.”

About the VA Million Veteran Program

Launched in 2011, MVP is a landmark research effort aimed at better
understanding how genes affect health. Up to a million Veterans are expected
to enroll in the VA study over the next 5-6 years. Data and genetic samples
collected through the study are stored securely and made available for studies
by authorized researchers, with stringent safeguards in place to protect
Veterans’ private health information. MVP is now enrolling at over 40 VA
medical centers nationwide. The VA’s central bio-repository is equipped with a
state-of-the-art robotic system for DNA extraction and storage and is
currently being expanded to support up to 4 million samples. With more than
135,000 enrollees to date, MVP already far exceeds the enrollment numbers of
any single VA study or research program in the past.

MVP provides researchers with a rich resource of genetic, health, lifestyle,
and military-exposure data collected from questionnaires, medical records, and
genetic analyses. By combining this information into a single database, MVP
promises to advance knowledge about the complex links between genes and

Veterans’ privacy and confidentiality are top priorities in MVP, as in all VA
research. For more information about MVP, visit

About Personalis

Personalis provides researchers and clinicians accurate DNA sequencing and
interpretation of human genomes. We support researchers engaging in
case-control, family-based, or proband-only genome studies of disease,
pharmacogenomics, and cancer. Our ACE (Accuracy and Content Enhanced)
Technology™ can supplement a standard exome or genome, substantially
increasing its medically-relevant coverage and accuracy. Personalis builds on
this foundation with innovative algorithms and proprietary databases for
alignment, variant calling, annotation, and analysis. With this combination,
we provide genomic data and interpretation of the highest accuracy.


Personalis, Inc.
Carol Tillis, 1-650-752-1300
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