Merck Announces Appointment of Roger M. Perlmutter, M.D., Ph.D., As President of Merck Research Laboratories; Peter S. Kim,

  Merck Announces Appointment of Roger M. Perlmutter, M.D., Ph.D., As
  President of Merck Research Laboratories; Peter S. Kim, Ph.D., to Retire

Business Wire

WHITEHOUSE STATION, N.J. -- March 7, 2013

Merck (NYSE: MRK), known as MSD outside the United States and Canada, today
announced the appointment of Roger M. Perlmutter, M.D., Ph.D., as executive
vice president and president of Merck Research Laboratories (MRL), effective
April 15. Dr. Perlmutter will succeed Peter S. Kim, Ph.D., who has served in
the role since 2003. To ensure a seamless transition, Dr. Perlmutter and Dr.
Kim will work closely together for an initial period, after which Dr. Kim will
remain with the company as an advisor until his retirement in August.

Roger M. Perlmutter (Photo: Business Wire)

Roger M. Perlmutter (Photo: Business Wire)

“Roger is a world-class physician-scientist with a proven track record of
leading large research organizations and delivering a broad and diverse
pipeline of medicines,” said Kenneth C. Frazier, chairman and chief executive
officer, Merck. “With his deep knowledge of the ongoing changes in the
industry’s external environment and their implications for how we use R&D
resources, Roger is ideally suited to lead Merck’s global research and
development. I am confident that under Roger’s leadership, Merck will continue
to build upon our legacy of translating cutting edge science into medically
important products that make a difference for patients.”

Dr. Perlmutter was executive vice president and head of R&D at Amgen Inc. from
January 2001 to February 2012. During his tenure, Dr. Perlmutter oversaw the
development and subsequent approval of a number of novel biologic and small
molecule medicines in the areas of cancer, endocrinology, hematology,
inflammation and osteoporosis. Prior to joining Amgen, he was executive vice
president of worldwide basic research and preclinical development at Merck. He
joined Merck as a senior vice president in February 1997.

Before assuming leadership roles in industry, Dr. Perlmutter was a professor
in the Departments of Immunology, Biochemistry and Medicine at the University
of Washington, where he also served as chairman of the Department of
Immunology and was a Howard Hughes Medical Institute investigator. He is a
Fellow of the American Academy of Arts and Sciences and an elected Fellow of
the American Association for the Advancement of Science. Dr. Perlmutter
graduated from Reed College in 1973 and received his M.D. and Ph.D. degrees
from Washington University in St. Louis in 1979.

“I am honored to have the opportunity to return to Merck and to lead MRL,”
said Dr. Perlmutter. “Throughout my career, as both a physician and a
scientist, I have drawn inspiration from Merck’s unwavering commitment to
scientific excellence. Over time, this commitment has brought forth an
unparalleled number of breakthrough medicines and vaccines that improve the
lives of patients around the world.”

Mr. Frazier also reiterated Merck's commitment to delivering growth through
innovation. “Merck continues to focus on increasing the productivity of our
R&D investments to create value for patients, customers and shareholders,”
said Frazier. “Under Roger’s leadership, we will continue to build and expand
in key therapeutic areas, advance our promising late-stage candidates and
bring forth new therapeutic candidates that will fuel our future pipeline.”

Dr. Kim joined MRL as executive vice president, Research and Development in
2001 and was appointed president of MRL in 2003. Prior to joining Merck, he
served as a professor of biology at Massachusetts Institute of Technology and
was also a member of the Whitehead Institute and a Howard Hughes Medical
Institute investigator. While at Merck, Dr. Kim served as a member of the
Council of the Institute of Medicine of the National Academy of Sciences, a
member of the Board of Directors of the Whitehead Institute for Biomedical
Research and as a member of the Council of the Global HIV Vaccine Enterprise.

During Dr. Kim’s tenure, Merck gained approval of more than 20 new medicines
and vaccines that have sustained the company’s growth and significantly
improved global health. These include JANUVIA (sitagliptin), the first DPP-4
inhibitor for type 2 diabetes; GARDASIL [Human Papillomavirus Quadrivalent
(Types 6, 11, 16 and 18) Vaccine, Recombinant], the first vaccine for
prevention of cervical cancer; ISENTRESS (raltegravir), the first HIV
integrase inhibitor; ZOSTAVAX (zoster vaccine live), the first herpes zoster
vaccine for the prevention of shingles in adults; RotaTeq (Rotavirus Vaccine,
Live, Oral, Pentavalent), an oral vaccine for the prevention of rotavirus
infection in infants; and VICTRELIS (boceprevir), the first oral hepatitis C
protease inhibitor. As of Feb. 22, 2013, Merck has 38 candidates in late-stage
clinical development (Phase II and III).

“Peter has helped sustain Merck’s commitment to outstanding science and
innovation during a period of enormous change for our company and our
industry,” said Frazier. “His contributions have positioned us well for future
success. Over the past decade, Peter led MRL through an immense transition in
pharmaceutical research and development, oversaw important advances in our use
of new technologies, began leveraging external innovation and led the creation
of an integrated, industry-leading pipeline following our merger with
Schering-Plough.”

“I am deeply grateful to the incredibly talented and dedicated people of MRL
who have worked with me over the past 12 years on our mission of delivering
medicines and vaccines to improve human health around the world,” said Kim. “I
am very pleased with Roger’s appointment and confident that he is the right
person to lead MRL into the future, and am committed to ensuring a seamless
leadership transition for this truly special organization and its great
people.”

About Merck

Today's Merck is a global healthcare leader working to help the world be well.
Merck is known as MSD outside the United States and Canada. Through our
prescription medicines, vaccines, biologic therapies, and consumer care and
animal health products, we work with customers and operate in more than 140
countries to deliver innovative health solutions. We also demonstrate our
commitment to increasing access to healthcare through far-reaching policies,
programs and partnerships. For more information, visit www.merck.com and
connect with us on Twitter, Facebook and YouTube.

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This news release includes “forward-looking statements” within the meaning of
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Reform Act of 1995. These statements are based upon the current beliefs and
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manufacturing difficulties or delays; financial instability of international
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patents and other protections for innovative products; and the exposure to
litigation, including patent litigation, and/or regulatory actions.

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statement, whether as a result of new information, future events or otherwise.
Additional factors that could cause results to differ materially from those
described in the forward-looking statements can be found in Merck’s 2012
Annual Report on Form 10-K and the company’s other filings with the Securities
and Exchange Commission (SEC) available at the SEC’s Internet site
(www.sec.gov).

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