SHIRE PLC: Total Voting Rights

Total Voting Rights 
March 1, 2013 - Shire plc (LSE: SHP, NASDAQ: SHPG) (the "Company"), in
accordance with DTR 5.6.1 of the FSA's Disclosure and Transparency Rules,
notifies the market of the following: 
At close of business on February 28, 2013, the Company's issued ordinary share
capital comprised 557,275,797 ordinary shares of 5 pence each with voting
rights and a further 5,296,070 ordinary shares held in treasury. 
Therefore the total number of voting rights in the Company is 557,275,797. This
is the figure which should be used by shareholders as the denominator for the
calculations by which they will determine if they are required to notify their
interest in, or a change to their interest in, the Company under the Financial
Services Authority's Disclosure and Transparency Rules. 
Tony Guthrie
Deputy Company Secretary 
For further information please contact: 
Investor Relations                                                              
Eric Rojas                         +1 781 482 0999    
Sarah Elton-Farr               +44 1256 894157    
Notes to editors 
Shire enables people with life-altering conditions to lead better lives. 
Through our deep understanding of patients' needs, we develop and provide
healthcare in the areas of: 
* Behavioral Health and Gastro Intestinal conditions 

      * Rare Diseases
      * Regenerative Medicine
    as well as other symptomatic conditions treated by specialist physicians.

We aspire to imagine and lead the future of healthcare, creating value for
patients, physicians, policymakers, payors and our shareholders.

Registered in Jersey, No. 99854, 22 Grenville Street, St Helier, Jersey JE4 8PX 
Press Release                                      
-0- Mar/01/2013 12:00 GMT
Press spacebar to pause and continue. Press esc to stop.