SHIRE PLC: Full Year 2012 Results Date Notification

Full Year 2012 results date notification - February 14, 2013 
Dublin, Ireland - February 1, 2013 - Shire plc (LSE: SHP, NASDAQ: SHPG), will
announce full year 2012 earnings on Thursday February 14, 2012. 
Results press release will be   12:00 GMT / 07:00 EST                          
issued at:                                                                      
                                                                           
Investor conference call time:  14:00 GMT / 09:00 EST                           
Live conference call for investors: 
Angus Russell, Chief Executive Officer and Graham Hetherington, Chief Financial
Officer will host the investor and analyst conference call at 14:00 GMT/9:00
EST. 
The details of the conference call are as follows: 
UK dial in:             08082370030 or 02031394830                         
                                                                           
US dial in:             1 866 928 7517 or 1 718 873 9077                    
                                                                           
International Access    
http://wpc.1726.planetstream.net/001726/FEL_Events_International_Access_List.pdf 
Numbers:                                                                        
                                                                           
Password/Conf ID:       99054603#                                          
                                                                           
Live Webcast:           
http://event.onlineseminarsolutions.com/r.htm?e=580771&s=1&k=FB534593ACC4ADF8B78
2C460E7624D98 
Replay: 
A replay of the presentation will be available for two weeks by phone and by
webcast for three months. Details can be found on our Investor Relations
website http://www.shire.com/shireplc/en/investors. 
For further information please contact: 
Investor Relations  Souheil Salah (ssalah@shire.com)         +44 1256 894 160   
                                                                            


                    Erin K. Kelly (erikelly@shire.com)       +1 781 482 9541   

Notes to editors

Shire enables people with life-altering conditions to lead better lives.

Through our deep understanding of patients' needs, we develop and provide
healthcare in the areas of:

  * Behavioral Health and Gastro Intestinal conditions
      * Rare Diseases
      * Regenerative Medicine
    as well as other symptomatic conditions treated by specialist physicians.

We aspire to imagine and lead the future of healthcare, creating value for
patients, physicians, policymakers, payors and our shareholders.

For further information on Shire, please visit the Company's website: 
www.shire.com.
                                                                              2

Registered in Jersey, No. 99854, 22 Grenville Street, St Helier, Jersey JE4 8PX

Press Release                                   


                                            
www.shire.com                                    
END 
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