Wolters Kluwer Health, The Altos Group Highlight Long-Term Impact of Change Management on Sepsis Mortality Rates among

  Wolters Kluwer Health, The Altos Group Highlight Long-Term Impact of Change
  Management on Sepsis Mortality Rates among California Hospital Cohort

Business Wire

MINNEAPOLIS -- January 15, 2013

Wolters Kluwer Health, a leading global provider of information for healthcare
professionals and students, announced today that nine California hospitals
have maintained a 50% sepsis mortality rate reduction two years after
participating in a change management study. The company has integrated key
elements of the study, which was designed and led by its strategic partner,
The Altos Group, into a ground-breaking sepsis mortality reduction program.

As part of the California study, which was profiled by the Agency for
Healthcare Research and Quality (AHRQ), participating hospitals adopted four
common approaches: 1) sepsis screening of all patients, 2) a fast-track workup
to confirm the diagnosis, 3) initiatives to promote adherence to protocols
that call for prompt initiation of appropriate treatment, and 4) ongoing
monitoring. The result was a 54.5% reduction in average mortality rates within
three years of the study’s launch in December 2008.

In December 2012, all nine hospitals reported continued declines in mortality
rates. Additionally, the overall cohort-wide mortality rate was down 49.8%
relative to the baseline. The same change management model was also studied
for its impact on medication error rates. The resulting 89% improvement was
also maintained years after the active phase of the program ended.

“These results demonstrate the validity of a change-management approach to
sepsis reduction,” said Julie A. Kliger, MPA, BSN, president and CEO, The
Altos Group. “Equally important, these outcomes were maintained over a
significant period of time. That is vital in healthcare, where sustaining
improvement is as desired as it is elusive.”

Wolters Kluwer Health’s sepsis mortality reduction program focuses on early
detection and applying best practices to treating the septic patient. In
addition to reducing overall patient mortality, costs and lengths of stay, the
goal of the program is to identify and address the top healthcare-associated
infections (HAI) that drive sepsis mortality. This will be accomplished
through a three-pronged approach that couples mobile software with actionable
content supplemented by change management consulting services. The program is
driven by Wolters Kluwer Health’s trusted brands including UpToDate^®,
Lexicomp^®, ProVation^® Order Sets, and Sentri7^®.

“Efficacy and sustainability are powerful motivators for clinicians who are
being asked to adopt new clinical practices and workflows. Physicians want to
make sure that the things they are being asked to do actually improve patient
care,” said Linda R. Peitzman, M.D., Chief Medical Officer, Wolters Kluwer
Health, Clinical Solutions. “Though change management represents just one
element of our sepsis mortality reduction program, this demonstration of its
long-term impact is validation that an approach to disease management that
looks at multiple aspects of both the system and workflow is the right path to
follow.”

Hospitals are currently being enrolled to serve as pilot sites in the program.
Interested facilities should contact Andy Strunk, Innovation Lab Program
Director, at (650) 224-4463 or andy.strunk@wolterskluwer.com.

About Wolters Kluwer Health
Wolters Kluwer Health (Philadelphia, PA) is a leading global provider of
information, business intelligence and point-of-care solutions for the
healthcare industry. Serving more than 150 countries and territories
worldwide, Wolters Kluwer Health’s customers include professionals,
institutions and students in medicine, nursing, allied health and pharmacy.
Major brands include traditional publishers of medical and drug reference
tools, journals and textbooks, such as Lippincott Williams & Wilkins; and
electronic information providers, such as Ovid^®, Medknow, UpToDate^®,
Medi-Span^®, Facts & Comparisons^®, Pharmacy OneSource^®, Lexicomp^® and
ProVation^® Medical.

Wolters Kluwer Health is part of Wolters Kluwer, a market-leading global
information services company. Wolters Kluwer has 2011 annual revenues of €3.4
billion ($4.7 billion), employs approximately 19,000 people worldwide, and
maintains operations in over 40 countries across Europe, North America, Asia
Pacific, and Latin America.

About The Altos Group
The Altos Group’s mission is to improve patient outcomes by creating highly
trained, motivated and engaged frontline practitioners. Our work has produced
results that directly correlate to a significant reduction in overall sepsis
mortality and medication errors. In addition to improved patient outcomes and
satisfaction, our clients have witnessed improved staff satisfaction,
retention, recruitment and professionalism.

The Altos Group works with healthcare providers to create programs that are
specifically designed to improve clinical, as well as operational, outcomes.
Our proven programs are results-oriented, creating a culture of learning and
accountability that translates into better patient outcomes, a professionally
fulfilled staff and improved financial performance.

Contact:

Wolters Kluwer Health | Clinical Solutions
Media Contact:
Cheri Palmer, 612-217-5253
Vice President, Commercial Programs
cheri.palmer@wolterskluwer.com