Akonni Biosystems Expands Family of TruTip Extraction Products for Hamilton Microlab STAR Line of Liquid Handling Workstations

  Akonni Biosystems Expands Family of TruTip Extraction Products for Hamilton
  Microlab STAR Line of Liquid Handling Workstations

   “Smart-tip” approach for rapidly generating high quality human gDNA now
        supports extraction from tissue, buffy coat, cells and saliva

Business Wire

FREDERICK, Md. -- January 14, 2013

Akonni Biosystems today announced it has extended its family of “smart-tip”
extraction products for rapidly purifying human genomic deoxyribonucleic acid
(gDNA) on the Hamilton Microlab^® STAR™ line of robotic liquid handling
workstations. The first product in the family of gDNA kits provides laboratory
technicians with the ability to process up to 300 µL of fresh or frozen whole
blood. This kit now has the added capability to be used to process other
sample types including buffy coat, tissue, buccal swabs and cells. For all
sample types, this kit delivers superior quality gDNA simultaneously from
eight to 96 samples in less than 60 minutes.

The second TruTip® gDNA kit now available supports the extraction and
concentration of gDNA for up to 400 µL of saliva collected using Oragene®
DISCOVER Collection Kit from DNA Genotek, Inc., a subsidiary of OraSure
Technologies, Inc. (NASDAQ: OSUR). Given the non-invasive nature of collecting
gDNA from saliva samples compared to blood, this sample type is commonly used
for very large-scale genetic studies, such as for breast cancer research.

TruTip extraction kits running on Hamilton Microlab STAR system do not require
a magnetic head, vacuum manifold, centrifuge, or other space-consuming or
expensive capital equipment. Both TruTip gDNA Kits can be used with a variety
of backend analytical tools, including qPCR, real time PCR, digital PCR,
microarrays, and mid-multiplex bead-based systems, as well as traditional and
next-generation sequencing systems.

“The Akonni TruTip line of products are simple to use with our workstations
and save our customers time while ensuring reliable results by reducing the
amount of hands-on steps to extract gDNA prior to performing complex
analytics,” said Bobby Chavli, Associate Director of Marketing and Business
Development at Hamilton Robotics. “It is terrific to see a rapid succession of
new 'smart-tips' to match our customer’s requirements.”

“TruTip is an industry-first smart consumable for sample preparation created
specifically to reduce bottlenecks in high-throughput genetic testing. By
adding the ability to extract DNA from tissue, cells and saliva, we now have
wide coverage across the sample types most commonly used for downstream
genetic-based research,” states Kevin Banks, Ph.D., Vice President Strategic
Development at Akonni Biosystems. Banks adds, “We are excited to continue
expanding our TruTip line of products running on liquid handling workstations
manufactured by Hamilton Robotics, as these systems are universally recognized
as being the most reliable and highest performing in the industry.”

Akonni Biosystems will be presenting a poster at the Society for Laboratory
Automation and Screening conference (SLAS2013) entitled "SmartTip" Approach to
Automated Genomic DNA Extraction using Akonni TruTip Technology on Hamilton
Microlab STAR Liquid Handling Workstation on  Monday, January 14, 1:00 – 3:00
PM (MP080).

About TruTip Extraction Kits

The patented TruTip family of products uses a porous nucleic acid binding
matrix embedded in a pipette tip and extracts DNA or Ribonucleic acid (RNA)
using well-understood chaotropic salt chemistry. These new kits for gDNA
enable completion of the entire extraction process, including a fully
automated onboard heat incubation step, in less than an hour and are four to
five times faster than most traditional high-throughput approaches. TruTip
delivers “gold-standard-equivalent" yields with superior purity and
reproducibility. These kits are currently released for RUO.

About Akonni Biosystems

Akonni is a developer of highly innovative products and technologies designed
to significantly increase productivity in the life science tools market
(“Sample Prep Market”) and to dramatically lower the cost of testing in the
molecular diagnostics market (“MDx Market”). Akonni Biosystems was founded in
2003 and has over 48 patents issued or pending. Supported by a series of
government grants and contracts from NIH, CDC, DOE, DOD, NIJ, and NSF, the
company has significantly advanced the original technology by improving its
capabilities from sample preparation to final result. Commercial products and
those in its near-term pipeline include rapid sample preparation methodologies
for nucleic acid extraction and mid-multiplex panel assays for detecting
multidrug-resistant tuberculosis (MDR-TB), upper respiratory infections, viral
encephalitis, and healthcare-associated infections (MRSA). For more
information, visit www.akonni.com.

About Hamilton Robotics

Hamilton is a leading worldwide supplier of precision liquid handling
equipment, laboratory automation and storage systems, serving customers in
academic and private research laboratories, pharmaceutical and clinical
diagnostic companies and governmental institutions. Hamilton maintains
headquarters in Reno, Nevada and Bonaduz, Switzerland, both of which house R&D
and production facilities. Hamilton has subsidiaries for direct sales and
service in many countries and works with a wide distributor network in other
regions. Hamilton is a privately held company. For more information, visit


For Akonni Biosystems:
Kevin Banks, 301-698-0101 ext. 287
For Hamilton Robotics
Bobby Chavli, 775-858-2000 ext. 540
GeneCom Group
Annette Summers, 925-519-0608
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