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Amarin Announces U.S. Patent 8,324,195 Issuance for Vascepa(R)

Amarin Announces U.S. Patent 8,324,195 Issuance for Vascepa(R)

Issuance for 13/349,150 Application

BEDMINSTER, N.J. and DUBLIN, Ireland, Dec. 4, 2012 (GLOBE NEWSWIRE) -- Amarin
Corporation plc (Nasdaq:AMRN), a biopharmaceutical company focused on the
commercialization and development of therapeutics to improve cardiovascular
health, announced today that the U.S. Patent and Trademark Office (USPTO) has
issued a patent covering Amarin's Vascepa^® (icosapent ethyl) capsules based
on U.S. Patent Application Serial No. 13/349,150. On September 10, 2012,
Amarin announced the issuance of a Notice of Allowance for claims under this
application. The newly issued patent, U.S. Patent No.8,324,195, has a term
that expires no earlier than in 2030.

"This patent issuance represents yet another step forward in Amarin's effort
to protect the commercial potential of Vascepa," said Joseph Zakrzewski,
Amarin's Chairman and Chief Executive Officer. "Amarin's goal is to protect
the commercial potential of Vascepa to beyond 2030 through patent protection,
regulatory exclusivity and trade secrets and by taking advantage of
manufacturing barriers to entry."

Amarin now has 10 U.S. patents either issued or allowed as well as over 30
additional patent applications currently in prosecution in the United States.
Amarin is also pursuing patent applications related to Vascepa in multiple
jurisdictions outside the United States, including the application for
Amarin's MARINE method of use patent in Europe for which Amarin has announced
receipt of an Intention to Grant letter.

About Amarin

Amarin Corporation plc is a biopharmaceutical company focused on the
commercialization and development of therapeutics to improve cardiovascular
health. Amarin's product development program leverages its extensive
experience in lipid science and the potential therapeutic benefits of
polyunsaturated fatty acids. Vascepa^® (icosapent
ethyl),Amarin'sfirstFDAapproved product, is a patented, ultra pure omega-3
fatty acid product comprising not less than 96%EPA. For more information
about Vascepa visit www.vascepa.com. For more information about Amarin visit
www.amarincorp.com.

The Amarin Corporation plc logo is available at
http://www.globenewswire.com/newsroom/prs/?pkgid=13817

Forward-looking statements

This press release contains forward-looking statements, including statements
about whether certain issued patents would adequately protect Vascepa against
competition, Amarin's plan to protect the commercial potential of Vascepa, and
the future status of patent applications under review by the United States
Patent and Trademark Office. These forward-looking statements are not promises
or guarantees and involve substantial risks and uncertainties. Among the
factors that could cause actual results to differ materially from those
described or projected herein include the following: events that could
interfere with the continued validity or enforceability of a patent or the
issuance of a patent if not yet issued; Amarin's ability generally to maintain
adequate patent protection and successfully enforce patent claims against
third parties; commercializing Vascepa without violating the intellectual
property rights of others; and uncertainties associated generally with
research and development, clinical trials and related regulatory approvals and
exclusivity grants. A further list and description of these risks,
uncertainties and other risks associated with an investment in Amarin can be
found in Amarin's filings with the U.S. Securities and Exchange Commission,
including its most recent Quarterly Report on Form 10-Q. Existing and
prospective investors are cautioned not to place undue reliance on these
forward-looking statements, which speak only as of the date hereof. Amarin
undertakes no obligation to update or revise the information contained in this
press release, whether as a result of new information, future events or
circumstances or otherwise.

CONTACT: Amarin Contact Information:
         Stephen D. Schultz
         Senior Director, Investor Relations
         and Corporate Communications
         Amarin Corporation
         In U.S.: +1 (860) 572-4979 x292
         investor.relations@amarincorp.com

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