Vertex Announces Webcasts of its Presentations at Two Investor Conferences

  Vertex Announces Webcasts of its Presentations at Two Investor Conferences

Piper Jaffray Healthcare Conference 2012

Business Wire

CAMBRIDGE, Mass. -- November 16, 2012

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced that Vertex
will webcast its presentation at the 24^th Annual Piper Jaffray Healthcare
Conference on Tuesday, November 27, 2012 at 12:00 p.m. EST and at the NASDAQ
OMX 29^th Investor Program on Tuesday, December 4, 2012 at 2:15 p.m. GMT
(10:15 a.m. EST).

The presentations will be webcast live and may be accessed from the ‘Events &
Presentations’ link under the ‘Investors’ tab on the home page of Vertex’s
website at www.vrtx.com. A replay of the webcasts will also be available on
the Company’s website for two weeks following the presentations. To ensure a
timely connection, it is recommended that users register at least 15 minutes
prior to the scheduled webcast.

About Vertex

Vertex creates new possibilities in medicine. Our team discovers, develops and
commercializes innovative therapies so people with serious diseases can lead
better lives.

Vertex scientists and our collaborators are working on new medicines to cure
or significantly advance the treatment of hepatitis C, cystic fibrosis,
rheumatoid arthritis and other life-threatening diseases.

Founded more than 20 years ago in Cambridge, Mass., we now have ongoing
worldwide research programs and sites in the U.S., U.K. and Canada. Today,
Vertex has more than 2,000 employees around the world, and for three years in
a row, Science magazine has named Vertex one of its Top Employers in the life
sciences.

Vertex's press releases are available at www.vrtx.com.

(VRTX-WEB)

Contact:

Vertex Pharmaceuticals Incorporated
Kelly Lewis, 617-961-7530
Director, Investor Relations