Martha Rook Honored with a Silver Stevie® Women in Business Award for Best New Product of the Year

  Martha Rook Honored with a Silver Stevie® Women in Business Award for Best
  New Product of the Year

  *Martha recognized for her innovative approach to stem-cell scale-up
    production using the Mobius® CellReady 3L bioreactor
  *Award recognizes innovation and leadership among women executives and
    entrepreneurs worldwide

Business Wire

BILLERICA, Mass. -- November 14, 2012

EMD Millipore, the Life Science division of Merck KGaA of Darmstadt, Germany
announced today that employee Martha Rook has received a Silver Stevie® Award
for Women in Business in the category of Best New Product for her use of the
Mobius® CellReady Bioreactor to develop stem-cell scale-up production. Martha
led her team to use an innovative method to develop large quantities of stem
cells which are necessary for the development of therapeutic processes,
applications and clinical trials.

EMD Millipore Employee Martha Rook Honored with a Silver Stevie(R) Women in
Business Award for Best ...

EMD Millipore Employee Martha Rook Honored with a Silver Stevie(R) Women in
Business Award for Best New Product of the Year (Photo: Business Wire)

“This award recognizes women who lead innovation in their industries, “ said
Andrew Bulpin, Head of EMD Millipore’s Process Solutions Business Unit. “We
are delighted to have Martha as part of our organization, and we congratulate
her for receiving this prestigious recognition. Her leadership and innovative
work in scale-up stem cell production brings great value not only to EMD
Millipore, but to our customers and the life sciences industry as well.”

Stem cells have the potential to yield consistent sources of differentiated
cell types which can be leveraged for therapeutic purposes and for
facilitating and improving a number of drug discovery and development
processes. Industrial production of stem cells on a larger scale is essential
for driving forward research and clinical trials.

Typically, large scale production of stem cells is achieved using 2D tissue
culture vessels which can be an expensive and time consuming process for
researchers. Under Martha’s leadership, the Upstream & Sensor Technologies
group in EMD Millipore’s Process Solutions Business Unit took an innovative
approach to this industry challenge. The team used an established EMD
Millipore product- the Mobius® CellReady 3L bioreactor- and combined it with a
microcarrier scaffold for suspension expansion of human mesenchymal stem cells
(hMSCs) to study their potential for stem cell scale-up production. The stem
cells produced were identical to those produced with the traditional method,
but required less cost, time, and effort. Expansion of hMSCs in stirred tank
bioreactors using microcarriers is the first step to establishing a scalable,
single use and efficient production process.

As a result of Rook’s research, EMD Millipore is currently involved in
collaborating with smaller biotechnology companies and large clinical academic
centers’ customers that are using the Mobius® CellReady 3L Bioreactor for
large-scale production of stem cells.

The Stevie® American Business Awards are the world’s premier awards for women
executives, entrepreneurs and the organizations they run. The New Product &
Service Category recognizes new products and services introduced to the
marketplace since July 1, 2011 created by or for women. Judged by a panel of
over 200 executive from around the world, finalists are recognized with Gold,
Silver or Bronze award for their achievements. Recipients were honored at the
2012 Stevie® Awards for Women in Business awards dinner and in New York City
on Friday, November 9.

Martha received her Ph.D. in Biochemistry from MIT and B.S. in Chemistry from
Texas A&M University. Martha pursued post-doctoral studies in neuroscience at
Harvard Medical School. She has worked in clinical diagnostics at Variagenics,
a pharmacogenomics company, and Quest Diagnostics as a Genomics and Esoteric
Testing Specialist before joining EMD Millipore in 2005. Martha is currently
Head of Upstream and Sensor Technologies within the Process Solutions business
unit at EMD Millipore.

About EMD Millipore

EMD Millipore is the Life Science division of Merck KGaA of Germany and offers
a broad range of innovative, performance products, services and business
relationships that enable our customers' success in research, development and
production of biotech and pharmaceutical drug therapies. Through dedicated
collaboration on new scientific and engineering insights, and as one of the
top three R&D investors in the Life Science Tools industry, EMD Millipore
serves as a strategic partner to customers and helps advance the promise of
life science.

Headquartered in Billerica, Massachusetts, the division has around 10,000
employees, operations in 67 countries and 2011 revenues of EUR 2.4 billion.
EMD Millipore is known as Merck Millipore outside of the U.S. and Canada.

Note: Merck KGaA or Merck shall mean Merck KGaA, Darmstadt, Germany

About Merck

All Merck Press Releases are distributed by e-mail at the same time they
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Merck is a global pharmaceutical and chemical company with total revenues of €
10.3 billion in 2011, a history that began in 1668, and a future shaped by
more than 40,000 employees in 67 countries. Its success is characterized by
innovations from entrepreneurial employees. Merck's operating activities come
under the umbrella of Merck KGaA, in which the Merck family holds an
approximately 70% interest and shareholders own the remaining approximately
30%. In 1917 the U.S. subsidiary Merck & Co. was expropriated and has been an
independent company ever since.

About the Stevie® Awards

Stevie® Awards are conferred in four programs: The American Business Awards,
The International Business Awards, the Stevie® Awards for Women in Business,
and the Stevie® Awards for Sales & Customer Service. Honoring organizations of
all types and sizes and the people behind them, the Stevies recognize
outstanding performances in the workplace worldwide. Learn more about The
Stevie Awards at www.stevieawards.com.

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Contact:

EMD Millipore
Jennifer Bianco, +1-978-715-1594
Jennifer.Bianco@emdmillipore.com
 
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