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BRAVE Awards Recipients Announced



                      BRAVE Awards Recipients Announced

  PR Newswire

  DUBLIN, November 14, 2012

DUBLIN, November 14, 2012 /PRNewswire/ --

- Fifteen everyday heroes who selflessly care for others in the face of
adversity honored by Shire in annual international awards program

They inspire with their determination, selflessness, courage and hope.
 Fifteen caregivers from around the world have been announced today as
Recipients or Distinguished Honorees in the 2 ^nd Annual Shire BRAVE Awards,
an international program that honors the bravery and devotion of
non-professional caregivers. Launched by Shire in 2011, the BRAVE Awards are
the first and only initiative of its kind and are designed to celebrate the
amazing commitment of unsung everyday heroes - caregivers - who provide
consistent and dedicated care for others.

"Our BRAVE Award winners represent the invisible army of millions of family
caregivers, many of whom balance a job, household tasks and the intense
medical needs of another person, and in many case, several people," said Angus
Russell, Shire Chief Executive Officer. "Their consistent care of others is an
enormously generous way to live their life, and we at Shire are privileged to
recognize these individuals who bravely overcome unimaginable obstacles and
work tirelessly to give their loved ones as normal and healthy a life as
possible."

Shire received more than 550 nominations for the 2012 BRAVE Awards from 10
countries over the 15 week nomination period. The nominations were reviewed
and ranked by the BRAVE Awards Selection Committee, including select Shire
employees from around the world and two external and independent experts in
the area of caregiving.  The experts who supported the selection process for
2012 were Frank Goodwin, Secretary of EuroCarers, the European association
that works on behalf of unpaid caregivers; and Gary Barg, Founder and Editor
in Chief of Today ' s Caregiver and author of The Fearless Caregiver.  

"The BRAVE Awards is a unique international program that not only recognizes
these specific carers but which also importantly raises awareness of the role
non-professional caregivers play in our society everyday," said Mr. Goodwin.

Nominations were ranked based on the qualities that define Shire's own BRAVE
culture: respect, courage, dedication, impact and patience. Shire's 5,200
global employees helped to select the Recipients and Distinguished Honorees
from the pool of eligible finalists.  The ten Recipients of a 2012 BRAVE Award
each will receive $10,000 USD or the local currency equivalent, and the five
Distinguished Honorees will each be awarded $2,500 USD or the local currency
equivalent.  

"Providing resources and support for caregivers is a constant focus for those
of us who serve these dedicated healthcare heroes. This unique awards
initiative recognizes and celebrates family caregivers who fearlessly advocate
for the wellbeing of their loved ones, often drawing strength and spirit from
the very people for whom they care," said Mr. Barg.

To read more about and hear from each of the 2012 BRAVE Awards Recipients and
Distinguished Honorees, visit http://www.ShireBRAVEAwards.com

2012 BRAVE AWARDS RECIPIENTS:

Brian Burke ( Santa Rosa ,   CA ): Thanks to Brian's love, support and care,
his wife Kate, who was diagnosed with a stage IV brain tumor, breast cancer
and suffered a severe stroke, has beaten the odds, living well beyond her
prognosis and providing hope for countless cancer and stroke survivors.

Carmen Carrasco Lobato ( Malaga ,   Spain ): Carmen a mother of five, has
dedicated more than 43 years of her life to care for her three sons and
recently, a family friend, all of who were born with serious development
disabilities.  She goes well above and beyond the role of mother and friend.

Patsy Fleckenstein ( Baltimore ,   MD ): For nearly two decades, Patsy has
served as the inspiring matriarch of her family, caring full-time for her two
grown children (and their four kids) after separate car accidents left them
both paralyzed from the neck down.

Debra Frain ( Cheektowaga ,   NY ): Thanks to Debra's tireless devotion and
refusal to give up, her 21-year-old son Matt, who suffers from a rare
neuromuscular disease and is confined to a wheelchair, is halfway through
college, having lived well past the 12 months that doctors originally
forecasted.

Randall Gregory (Beverly, MA): After Randall's wife Nicole suffered a stroke
that left her paralyzed from the neck down just one year into their marriage,
he has provided constant emotional, physical and financial support for the
woman he calls his wife and best friend, striving daily to give Nicole as
normal a life as possible.

Carol Harmer ( Wagga Wagga ,   Australia ) : Carol is a full-time mother and
full-time caregiver for her three children, two of whom have Phelan-McDermid
syndrome (PMS) and are fully dependent for basic needs.  She also finds time
to be an advocate, helping raise awareness about children with special needs.

Raul Navarro (Corona, CA): Raul has served as his wife Mary's 24/7 caregiver
for nearly 25 years despite his own battle with cancer, trading in his
well-paying job to help her through two bouts of thyroid cancer, seizures and
Amyotrophic Lateral Sclerosis (ALS).

Mary Pizzurro ( Tampa ,   FL ): Mary has spent the past 21 years caring for
her four children, two of whom suffer from giant axonal neuropathy (GAN), a
disease with no cure that causes Michael and Joseph to use power wheelchairs,
feeding tubes and tracheotomies.  She is also pursuing a nursing degree,
inspiring her two daughters to follow in her footsteps.

Chelsea Scheiber (Rio   Oso ,   CA ): By refocusing her career and relocating
to care for her younger brother and best friend Travis, who has Becker
Muscular Dystrophy (BMD), Chelsea is the very definition of a selfless sister.

Otis Williams ( Jackson ,   MS ): A family hero, Otis works evenings so he can
take care of his family full-time when they're awake. His wife Michelle and
two of their three children have Charcot-Marie-Tooth disease (CMT), a form of
muscular dystrophy.

2012 BRAVE AWARDS DISTINGUISHED HONOREES:

William Dent ( Oakland ,   CA ): Around-the-clock, 70-year-old Bill selflessly
cares for his son Darren, who has Amyotrophic Lateral Sclerosis (ALS) and
relies on a feeding tube and ventilator, all the while striving to put a smile
on Darren's face each day, as he knows laughter can be the best medicine.

Mark Jubinville ( Chicopee ,   MA ): For 30 years, Mark has selflessly fought
for his wife Lori after she had a stroke during pregnancy and three subsequent
strokes that left her paralyzed on her left side.  He also researched a
potential solution to prevent future strokes, all the while raising their son.

Catherine O ' Hare ( Birmingham ,   AL ): Catherine's extraordinary level of
passion, humility and commitment to her 18-year-old daughter Amelia, who was
diagnosed with spinal muscular atrophy (SMA) as a one-year-old, has allowed
Amelia to live a rich and fulfilling life, even though she cannot stand or
walk.

Daniel Steckman ( Holyoke ,   CO ): A great father and loving husband, Dan is
the primary caregiver for his son Jeremy, who suffers from muscular dystrophy,
and serves as the household leader, as his wife received a heart transplant
and has health restrictions.

Mary Sweeney ( Willis ,   TX ): Mary's husband Bill, who suffers from
Amyotrophic Lateral Sclerosis (ALS) and cannot walk or speak, has learned to
use an eye-gaze computer to communicate and does more than many able-bodied
men thanks to her endless care, love and encouragement over the past 15 years.

The Shire BRAVE Awards are presented in the spirit of Shire's BRAVE culture,
which fosters an environment that encourages its employees and partners to act
with integrity; create innovative solutions that make a difference; act on the
needs of others; strive to be better every day; and to exemplify trust and
openness through teamwork. Nominations for the 2013 Shire BRAVE Awards are
expected to be open on or about March 15, 2013.  

Notes to editors

About the Shire BRAVE Awards

The Shire BRAVE Awards is an international program created by Shire to honor
the courage and dedication of individual caregivers. For the Shire Brave
Awards, a caregiver is defined as an individual who is providing regular,
consistent care for another person(s). The caregiver cannot be a professional
healthcare provider and cannot be compensated in any formal way through their
efforts as a caregiver.  The caregiver can be a relative, neighbor, or friend
who gives their time, support, and compassion regularly, helping another
person(s) who is (partly or wholly) unable to care for themselves due to
health issues, injury, or other extenuating circumstance. For further
information on the Shire BRAVE Awards, including official rules, legal
disclosures, and privacy policy please visit http://www.ShireBRAVEAwards.com .

SHIRE PLC

Shire enables people with life-altering conditions to lead better lives.

Through our deep understanding of patients' needs, we develop and provide
healthcare in the areas of:

  * Behavioral Health and Gastro Intestinal conditions
  * Rare Diseases
  * Regenerative Medicine

as well as other symptomatic conditions treated by specialist physicians.

We aspire to imagine and lead the future of healthcare, creating value for
patients, physicians, policymakers, payors and our shareholders.

For further information on Shire, please visit the Company's website:
http://www.shire.com .

For further information please contact: Matthew Cabrey ( mcabrey@shire.com ),
+1-484-595-8248Beverly Volpe ( bvolpe@simonpr.com ), +1-215-545-4715
x24Jessica Mann ( jmann@shire.com ), +44-1256-894-280
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