OXFORD INSTRUMENTS PLC: Holding(s) in Company

For filings with the FSA include the annex                                      
For filings with issuer exclude the annex                                       
TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi                                 
1. Identity of the issuer or the underlying       Oxford Instruments plc       
issuer of existing shares to which voting                                      
rights are attached: ii                                                         
2. Reason for the notification (please tick the appropriate box or boxes):       
An acquisition or disposal of voting rights                               x     
An acquisition or disposal of qualifying financial instruments which           
may result in the acquisition of shares already issued to which voting         
rights are attached                                                             
An acquisition or disposal of instruments with similar economic effect    x    
to qualifying financial instruments                                             
An event changing the breakdown of voting rights                                
Other (please specify):                                                          


3. Full name of person(s) subject to  BlackRock, Inc.                          
the notification obligation: iii                                               

4. Full name of shareholder(s) (if                                             
different from 3.):iv                                                           
5. Date of the transaction and date   24th October 2012                        
on which the threshold is crossed or                                           
reached: v                                                                      
6. Date on which issuer notified:     25th October 2012                         
7. Threshold(s) that is/are crossed   Holding has gone below 14%               
or reached: vi, vii                                                             
8. Notified details: 
A: Voting rights attached to shares viii, ix 
Class/type of  Situation previous           Resulting situation after          
shares          to the triggering                 the triggering                
               transaction                     transaction                  
if possible               Number                 Number          % of voting   
using           Number      of      Number         of             rights x     
the ISIN CODE     of      Voting      of         voting                         

                Shares    Rights    shares       rights                        
                                    Direct  Direct  Indirect   Direct  Indirect
                                              xi       xii                     

GB0006650450   6,497,366 6,497,366   n/a      n/a   6,471,594   n/a     11.51%  
B: Qualifying Financial Instruments                                             
Resulting situation after the triggering transaction                            
Type of financial Expiration     Exercise/      Number of voting   % of voting  
instrument     date xiii  Conversion Period rights that may be    rights     

                                    xiv         acquired if the                
                                                 instrument is                 

C: Financial Instruments with similar economic effect to Qualifying Financial  
Instruments xv, xvi                                                            

Resulting situation after the triggering transaction                            
Type of      Exercise Expiration  Exercise/  Number of voting    % of voting  
 financial       price   date xvii  Conversion rights instrument  rights xix, 
  instrument                         period       refers to                      


 CFD                                           1,386,537       2.47%    
Total (A+B+C)                                                                   

        Number of voting rights               Percentage of voting rights      
               7,858,131                                13.98%                 

9. Chain of controlled undertakings through which the voting rights and/or the 
financial instruments are effectively held, if applicable: xxi                 

BlackRock Investment Management (UK) Limited - 7,858,131 (13.98%)               
Proxy Voting:                                                                   
10. Name of the proxy holder:                                                   
11. Number of voting rights proxy                                              
holder will cease to hold:                                                      
12. Date on which proxy holder will                                            
cease to hold voting rights:                                                    
13. Additional information:                     Oxford Instruments plc          
14. Contact name:                                 Susan Johnson-Brett           
15. Contact telephone number:                        01865 393 200              
-0- Oct/29/2012 11:11 GMT
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