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Infraredx and Philips Announce Collaboration to Develop a New Standard of Catheterization Lab Integration for True Vessel



  Infraredx and Philips Announce Collaboration to Develop a New Standard of
  Catheterization Lab Integration for True Vessel Characterization

 Companies to Produce New Offering that Combines Market Leading Cardiac X-ray
        Imaging System with Innovative Intravascular Imaging Platform

Business Wire

BURLINGTON, Mass. & ANDOVER, Mass. -- October 16, 2012

Infraredx, Inc., a medical device company committed to advancing the diagnosis
and management of coronary artery and other vascular diseases, and Royal
Philips Electronics (NYSE: PHG, AEX: PHIA) today announced they have signed a
joint development and collaboration agreement that is focused on integrating
Infraredx’s true vessel characterization (TVC) Imaging System with Philips’
Allura Xper catheterization (cath) lab imaging systems. This collaboration is
intended to enable seamless access to the TVC Imaging System with Philips’
Allura X-ray systems.

“Philips is the premier provider of X-ray imaging technology for
interventional cardiologists and we are pleased to partner with them on
developing this integrated solution,” said Don Southard, president and chief
executive officer of Infraredx. “Our goal is to offer physicians easier access
to the TVC Imaging System’s near-infrared spectroscopy and intravascular
ultrasound technology for use in determining the true extent of cardiovascular
disease, especially the presence of lipid core plaques (LCPs). The TVC Imaging
System is experiencing accelerated adoption in the U.S. and Europe. We believe
this growth is the result of mounting clinical evidence around the role of LCP
and continuous system enhancements.”

The joint product development is intended to provide physicians with tableside
control of the TVC Imaging System from within the sterile cath lab environment
using Allura’s table-mounted Xper module. The TVC Composite Image can be
viewed on the Philips’ cath lab monitors, enabling physicians to view the
Chemogram and intravascular ultrasound (IVUS) images alongside the coronary
angiogram. This will allow for better visualization of LCPs in a patient’s
coronary artery. The automatic sharing and integration of patient demographics
and imaging study information between the Allura system and the TVC system
will improve workflow efficiency and provide quicker retrieval and review of
information.

“As the global market leader in cath lab imaging technology, we strive to
offer advanced clinical applications that enable interventional procedures to
be performed more effectively,” said Bert van Meurs, senior vice president and
general manager, Interventional X-ray, Philips Healthcare. “The collaboration
with Infraredx supports our commitment to continuously improve the integrated
functioning of our cath labs and further enhance the user experience.”

About The TVC Imaging System™

The TVC Imaging System™ is a first-in-class intravascular imaging system that
holds the potential to revolutionize the management of coronary artery disease
by providing information that is critical for evaluating vessel structure and
composition, also known as true vessel characterization. The TVC Imaging
System helps interventional cardiologists identify which patients are prone to
complications during stenting. The device enables cardiologists to predict
peri-procedural heart attacks by assessing not only the degree of stenosis,
but also the presence and extent of lipid core plaques (LCP) of interest.

In a single pullback, the TVC Imaging System provides rapid and automated
detection of LCPs during the cardiac catheterization procedure. The device is
the only multimodality imaging system to combine both intravascular ultrasound
(IVUS) and near-infrared spectroscopy (NIRS). Through IVUS technology, the TVC
Imaging System provides clear and relevant information about vessel structure,
in real time. The system’s enhanced IVUS image provides a clear view of the
vessel and plaque, providing more reliable vessel interpretation and
assessment. The system’s NIRS technology enables interventional cardiologists
to reliably visualize the presence of LCP and predict the risk of
peri-stenting myocardial infarction. The multimodality images are obtained
simultaneously and require no post-processing or image manipulation. The TVC
Imaging System is the only device available in both the U.S. and Europe for
the detection of LCPs. Outside of the U.S., the TVC Imaging System is
available in more than 30 countries worldwide.

About Infraredx, Inc.

Infraredx, Inc. is a privately-funded medical device company dedicated to
helping provide practitioners with the information needed for enhanced
clinical decision making in treating coronary artery disease. The company is
committed to improving the safety and efficacy of coronary stenting and
ultimately serving as part of a strategy to prevent initial coronary events.
Through its TVC Imaging System™, Infraredx is changing the way coronary artery
disease is diagnosed and treated. The TVC Imaging System is the only
intravascular imaging system that enables true vessel characterization through
simultaneous structural and compositional imaging data obtained in a single
pullback. Through the use of both intravascular ultrasound (IVUS) and
near-infrared spectroscopy (NIRS) technologies, the system helps
interventional cardiologists identify which patients are prone to stenting
complications by assessing not only the degree of stenosis, but also the
presence of lipid core plaque. Founded in 1998, Infraredx is headquartered in
Burlington, Mass. For more information, visit www.infraredx.com.

About Royal Philips Electronics

Royal Philips Electronics (NYSE: PHG, AEX: PHIA) is a diversified health and
well-being company, focused on improving people’s lives through meaningful
innovation in the areas of Healthcare, Consumer Lifestyle and Lighting.
Headquartered in the Netherlands, Philips posted 2011 sales of EUR 22.6
billion and employs approximately 122,000 employees with sales and services in
more than 100 countries. The company is a leader in cardiac care, acute care
and home healthcare, energy efficient lighting solutions and new lighting
applications, as well as male shaving and grooming, home and portable
entertainment and oral healthcare. News from Philips is located at
www.philips.com/newscenter.

Contacts:

Contact:

Infraredx, Inc.
Grant Frazier, 781-345-9632
Vice President of Marketing
gfrazier@infraredx.com
or
Philips
Rachel Bloom-Baglin, 978-659-3748
Senior Director, Communications
Rachel.bloom-baglin@philips.com
or
Philips
Steve Klink, +31 6 10888824
Senior Press Officer
steve.klink@philips.com
or
Pure Communications, Inc.
Susan Heins (media), 864-286-9597
sjheins@purecommunicationsinc.com
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