Boston Scientific Announces FDA Approval and U.S. Launch of EPIC™ Vascular Stent

  Boston Scientific Announces FDA Approval and U.S. Launch of EPIC™ Vascular

New Self-Expanding Nitinol Stent Offers Balance of Flexibility and Radial
Strength for Enhanced Performance in Iliac Stenting Procedures

PR Newswire

NATICK, Mass., May 17, 2012

NATICK, Mass., May 17, 2012 /PRNewswire/ --Boston Scientific Corporation
(NYSE: BSX) announces U.S. Food and Drug Administration approval and market
launch of the Epic™ Vascular Self-Expanding Stent System. The Epic Stent is
designed to open blocked arteries in patients with iliac artery stenosis, a
form of peripheral vascular disease associated with severe leg pain caused by
insufficient blood flow.

"The Epic Stent System demonstrates an excellent combination of flexibility,
radial force and deployment accuracy - all important attributes when treating
challenging atherosclerotic lesions in the iliac arteries," said Thomas
Shimshak, M.D., medical director at Wheaton Franciscan Heart Care in Racine,
WI. "The comprehensive stent size matrix should also help meet a variety of
clinical requirements when treating iliac arterial disease with no compromise
in deliverability or stent performance."

The Epic Stent is a self-expanding Nitinol stent designed to sustain vessel
patency, while providing enhanced visibility and accuracy during placement.
It employs an innovative Tandem Architecture™, which is engineered to provide
excellent stent flexibility while maintaining predictable radial force
characteristics and fracture resistance. The Epic Stent employs distal and
proximal radiopaque markers and all stent sizes are compatible with 6F
sheaths. The stent delivery system is offered in two shaft lengths (75 cm and
120 cm) for all sizes and is compatible with 0.035" guidewires.

In January, Boston Scientific announced that the ORION trial met its primary
clinical endpoint. The Epic Vascular Stent System demonstrated a low
nine-month major adverse events (MAE) rate of 3.4 percent in the
intent-to-treat population, which was significantly lower than the
pre-specified performance goal of 17 percent (p<0.001) based on historical
published outcomes for iliac stenting.

"The Epic Stent is another example of our commitment to innovation in treating
peripheral vascular disease, a growing worldwide health concern," said Jeff
Mirviss, president of the Boston Scientific Peripheral Interventions
Division. "This next-generation stent expands our growing peripheral
interventions portfolio, complementing the leading Express® LD
balloon-expandable iliac stent, and offering physicians a versatile new option
to treat patients with challenging lesions in the iliac arteries."

Iliac stenosis (narrowing) occurs when plaque accumulates within the arteries
that supply blood to the legs, which can lead to poor blood flow, claudication
(leg pain) and other complications. The disease can be treated with
medication, surgery or angioplasty.

The Epic Vascular Self-Expanding Stent System received CE Mark approval and
was launched in Europe and other international markets in 2009.

About Boston Scientific

Boston Scientific is a worldwide developer, manufacturer and marketer of
medical devices that are used in a broad range of interventional medical
specialties. For more information, please visit:

Cautionary Statement Regarding Forward-Looking Statements

This press release contains forward-looking statements within the meaning of
Section 27A of the Securities Act of 1933 and Section 21E of the Securities
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regarding product performance, clinical outcomes, our business plans and
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CONTACT: Steven Campanini
 508-652-5740 (office)
 Media Relations
 Boston Scientific Corporation

 Sean Findlen
 617-520-7268 (office)
 Media Relations
 Weber Shandwick

 Sean Wirtjes
 508-652-5305 (office)
 Investor Relations
 Boston Scientific Corporation

SOURCE Boston Scientific Corporation
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