Nov. 2 (Bloomberg) -- Shares of the following companies had unusual moves in U.S. trading. Stock symbols are in parentheses, and prices are as of 4 p.m. in New York.

Amylin Pharmaceuticals Inc. (AMLN US) added 9.9 percent to $12.13, the biggest gain since March 31. Takeda Pharmaceutical Co. (TKPHY US), maker of the world’s best-selling diabetes drug, agreed to pay as much as $1 billion to Amylin to co-develop obesity treatments as it seeks to bolster declining sales.

Central Pacific Financial Corp (CPF US) dropped 21 percent to $1.11, the lowest price since at least 1987. The Honolulu- based bank fell for the third straight day after saying regulators will probably ask the company to strengthen capital and improve asset quality.

Dean Foods Co. (DF US) had the second-steepest decline in the S&P 500, falling 8.5 percent to $16.69. The biggest U.S. dairy processor forecast fourth-quarter profit of 36 cents a share. The average profit estimate of 13 analysts in a Bloomberg survey was 39 cents.

Denbury Resources Inc. (DNR US) had the biggest decline in the S&P 500, dropping 10 percent to $13.09. The U.S. oil and natural-gas producer said it will buy Encore Acquisition Co. for about $4.5 billion to add fields in the Rocky Mountains and Gulf of Mexico.

Domtar Corp. (UFS US) gained 8.2 percent, the most since Aug. 4, to $45.33. North America’s largest maker of paper for copiers and envelopes was raised to “overweight” from “neutral” at JPMorgan Chase & Co. Domtar was also raised to “top Pick” from “outperform” at RBC Capital Markets.

Ford Motor Co. (F US) had the biggest gain in the S&P 500, rising 8.3 percent to $7.58. The only major U.S. automaker to avoid bankruptcy posted net income of $997 million in the third quarter and its first operating profit since early 2008. Ford said it expects to be “solidly profitable” in 2011.

GTx Inc. (GTXI US) tumbled 49 percent, the most since the company went public in 2004, to $4.56. The company developing a drug to prevent broken bones in prostate cancer patients failed to win U.S. approval for the product.

Human Genome Sciences Inc (HGSI US) surged 35 percent to $25.28, the highest price since February 2002. The company’s experimental lupus drug Benlysta worked in a higher dose to reduce symptoms in a study.

InfoGroup Inc. (IUSA US) climbed 17 percent to $7.65 for its steepest gain since March 18. The provider of business and consumer-information databases is trying to sell itself, the Omaha World-Herald said, citing people familiar with the matter. InfoGroup said in a statement that no decisions have been made.

Las Vegas Sands Corp. (LVS US) lost 5.3 percent to $14.29, the first decline in three days. The casino company run by billionaire Sheldon Adelson may raise about $2.5 billion in Hong Kong’s biggest initial public offering this year to restart construction of stalled projects and repay debt.

LDK Solar Co. (LDK US) lost 23 percent, the most since November 2008, to $5.23. Q-Cells SE said it has terminated its December 2007 supply agreement with the Chinese company.

Motorola Inc. (MOT US) gained 5.4 percent to $9.03, the highest price since Sept. 16. The biggest U.S. mobile-phone was raised to “buy” from “hold” at Citigroup Inc., which said the company is introducing a “compelling” offer of handsets.

Research In Motion Ltd. (RIMM US) fell 5.1 percent to $55.74. The BlackBerry maker was cut to “sell” from “buy” at Citigroup.

Nice Systems Ltd. (NICE US) dropped 5.3 percent, the most since May 7, to $29.34. The maker of digital-recording surveillance products said third-quarter profit slid 28 percent as revenue fell.

Terra Industries Inc. (TRA US) rose 6.7 percent, the most since March 3, to $33.91. Rival fertilizer maker CF Industries Holdings Inc. (CF US) boosted its takeover bid to about $4.05 billion and added a cash portion.

Varian Medical Systems Inc. (VAR US) rose 5.4 percent, the most since Aug. 31, to $43.18. The maker of radiation equipment used to treat cancer was raised to “buy” from “hold” at Soleil Securities Group Inc. The 12-month target price is $52 per share.

YRC Worldwide Inc. (YRCW US) had the biggest decline in the Russell 2000, slumping 64 percent to $1.32. Trading was halted earlier today. The biggest U.S. trucker by sales said that it intends to launch an exchange offer this week, proposing that noteholders would exchange approximately $536.8 million in face value of notes plus accrued and unpaid interest for shares of common stock and new Class A convertible preferred stock.

To contact the reporter on this story: Rita Nazareth in New York at rnazareth@bloomberg.net

Last Updated: November 2, 2009 16:53 EST